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PARP1 interacts with HMGB1 and promotes its nuclear export in pathological myocardial hypertrophy
High-mobility group box 1 (HMGB1) exhibits various functions according to its subcellular location, which is finely conditioned by diverse post-translational modifications, such as acetylation. The nuclear HMGB1 may prevent from cardiac hypertrophy, whereas its exogenous protein is proven to induce...
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| Publicado no: | Acta Pharmacol Sin |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6786360/ https://ncbi.nlm.nih.gov/pubmed/30030529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0044-4 |
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