Integration of Multiple Data Sources for Gene Network Inference Using Genetic Perturbation Data

The inference of gene networks from large-scale human genomic data is challenging due to the difficulty in identifying correct regulators for each gene in a high-dimensional search space. We present a Bayesian approach integrating external data sources with knockdown data from human cell lines to in...

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Bibliographic Details
Published in:J Comput Biol
Main Authors: Liang, Xiao, Young, William Chad, Hung, Ling-Hong, Raftery, Adrian E., Yeung, Ka Yee
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc., publishers 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786343/
https://ncbi.nlm.nih.gov/pubmed/31009236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2019.0036
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