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Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice

Nicotinamide phosphoribosyltransferase (Nampt) is the rate-limiting enzyme of nicotinamide adenine dinucleotide (NAD) salvage biosynthesis in mammals, and is involved in fundamental physiological processes and pathophysiology of many diseases. Thus far, however, the role of Nampt in atherosclerosis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Kong, Yuan-yuan, Li, Guo-qiang, Zhang, Wen-jie, Hua, Xia, Zhou, Can-can, Xu, Tian-ying, Li, Zhi-yong, Wang, Pei, Miao, Chao-yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786310/
https://ncbi.nlm.nih.gov/pubmed/30833708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0207-3
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