Nicotinamide phosphoribosyltransferase aggravates inflammation and promotes atherosclerosis in ApoE knockout mice

Nicotinamide phosphoribosyltransferase (Nampt) is the rate-limiting enzyme of nicotinamide adenine dinucleotide (NAD) salvage biosynthesis in mammals, and is involved in fundamental physiological processes and pathophysiology of many diseases. Thus far, however, the role of Nampt in atherosclerosis...

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Udgivet i:Acta Pharmacol Sin
Main Authors: Kong, Yuan-yuan, Li, Guo-qiang, Zhang, Wen-jie, Hua, Xia, Zhou, Can-can, Xu, Tian-ying, Li, Zhi-yong, Wang, Pei, Miao, Chao-yu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786310/
https://ncbi.nlm.nih.gov/pubmed/30833708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-018-0207-3
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