A multicenter study on patients with multisystem Langerhans cell histiocytosis developing secondary hemophagocytic lymphohistiocytosis

BACKGROUND: Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm characterized by the presence of abnormal CD1a(+)CD207(+) histiocytes. Hemophagocytic lymphohistiocytosis (HLH) represents a spectrum of hyper-inflammatory syndromes typified by the dysregulated activation of the innate and a...

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Publicado no:Cancer
Main Authors: Chellapandian, Deepak, Hines, Melissa, Zhang, Rui, Jeng, Michael, van den Bos, Cor, López, Vicente Santa-María, Lehmberg, Kai, Sieni, Elena, Wang, Yini, Nakano, Taizo, Williams, James, Fustino, Nicholas, Astigarraga, Itziar, Dunkel, Ira J., Abla, Oussama, van Halteren, Astrid GS, Pei, Deqing, Cheng, Cheng, Weitzman, Sheila, Sung, Lillian, Nichols, Kim E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6786263/
https://ncbi.nlm.nih.gov/pubmed/30521100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31893
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