Nonanimal Models for Acute Toxicity Evaluations: Applying Data-Driven Profiling and Read-Across

BACKGROUND: Low-cost, high-throughput in vitro bioassays have potential as alternatives to animal models for toxicity testing. However, incorporating in vitro bioassays into chemical toxicity evaluations such as read-across requires significant data curation and analysis based on knowledge of releva...

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Bibliographische Detailangaben
Veröffentlicht in:Environ Health Perspect
Hauptverfasser: Russo, Daniel P., Strickland, Judy, Karmaus, Agnes L., Wang, Wenyi, Shende, Sunil, Hartung, Thomas, Aleksunes, Lauren M., Zhu, Hao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Environmental Health Perspectives 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785238/
https://ncbi.nlm.nih.gov/pubmed/30933541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP3614
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