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Anti-inflammatory effects induced by ultralow concentrations of bupivacaine in combination with ultralow concentrations of sildenafil (Viagra) and vitamin D3 on inflammatory reactive brain astrocytes

Network coupled cells, such as astrocytes, regulate their cellular homeostasis via Ca(2+) signals spread between the cells through gap junctions. Intracellular Ca(2+) release is controlled by different signaling pathways that can be stimulated by ATP, glutamate and serotonin (5-HT). Based on our fin...

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Vydáno v:PLoS One
Hlavní autoři: Hansson, Elisabeth, Skiöldebrand, Eva
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785114/
https://ncbi.nlm.nih.gov/pubmed/31596904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0223648
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