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Upregulation of GABA Neurotransmission Suppresses Hippocampal Excitability and Prevents Long-Term Potentiation in Transgenic Superoxide Dismutase-Overexpressing Mice
Cu/Zn superoxide dismutase (SOD-1) is a key enzyme in oxygen metabolism in the brain. Overexpression of SOD-1 in transgenic (Tg) mice has been used to study the functional roles of this enzyme in oxidative stress, lipid peroxidation, and neurotoxicity. We found that Tg-SOD-1 mice are strikingly less...
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| 出版年: | J Neurosci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
1999
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6784966/ https://ncbi.nlm.nih.gov/pubmed/10594078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-24-10977.1999 |
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