Effect of Intra-Articular Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With Osteoarthritis: The FORWARD Randomized Clinical Trial

IMPORTANCE: Sprifermin is under investigation as a disease-modifying osteoarthritis drug. OBJECTIVE: To evaluate the effects of sprifermin on changes in total femorotibial joint cartilage thickness in the more symptomatic knee of patients with osteoarthritis. DESIGN, SETTING, AND PARTICIPANTS: FORWA...

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Detalles Bibliográficos
Publicado en:JAMA
Autores principales: Hochberg, Marc C., Guermazi, Ali, Guehring, Hans, Aydemir, Aida, Wax, Stephen, Fleuranceau-Morel, Patricia, Reinstrup Bihlet, Asger, Byrjalsen, Inger, Ragnar Andersen, Jeppe, Eckstein, Felix
Formato: Artigo
Lenguaje:Inglês
Publicado: American Medical Association 2019
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784851/
https://ncbi.nlm.nih.gov/pubmed/31593273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2019.14735
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