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Moxetumomab pasudotox for hairy cell leukemia: preclinical development to FDA approval

Moxetumomab pasudotox (MP) is an immunotoxin that recently received US Food and Drug Administration (FDA) approval for the treatment of hairy cell leukemia (HCL) that has failed at least 2 prior lines of therapy, including a purine analog. MP is a recombinant immunotoxin that consists of an anti-CD2...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Blood Adv
Hauptverfasser: Lin, Adam Yuh, Dinner, Shira Naomi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784515/
https://ncbi.nlm.nih.gov/pubmed/31594764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000507
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