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Joint inference and alignment of genome structures enables characterization of compartment-independent reorganization across cell types

BACKGROUND: Comparisons of Hi–C data sets between cell types and conditions have revealed differences in topologically associated domains (TADs) and A/B compartmentalization, which are correlated with differences in gene regulation. However, previous comparisons have focused on known forms of 3D org...

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Bibliografske podrobnosti
izdano v:Epigenetics Chromatin
Main Authors: Rieber, Lila, Mahony, Shaun
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784335/
https://ncbi.nlm.nih.gov/pubmed/31594535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-019-0308-3
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