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N-linked glycan branching and fucosylation are increased directly in HCC tissue as determined through in situ glycan imaging.

Hepatocellular carcinoma (HCC) remains as the fifth most common cancer in the world and accounts for more than 700,000 deaths annually. Changes in serum glycosylation have long been associated with this cancer but the source of that material is unknown and direct glycan analysis of HCC tissues has b...

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Bibliographische Detailangaben
Veröffentlicht in:J Proteome Res
Hauptverfasser: West, Connor A., Wang, Mengjun, Herrera, Harmin, Liang, Hongyan, Black, Alyson, Angel, Peggi M., Drake, Richard R., Mehta, Anand S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784322/
https://ncbi.nlm.nih.gov/pubmed/30110170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00323
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