Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children

BACKGROUND: Despite improved diagnostics, pulmonary pathogens in immunocompromised children frequently evade detection, leading to significant mortality. Therefore, we aimed to develop a highly sensitive metagenomic next-generation sequencing (mNGS) assay capable of evaluating the pulmonary microbio...

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Vydáno v:Clin Infect Dis
Hlavní autoři: Zinter, Matt S, Dvorak, Christopher C, Mayday, Madeline Y, Iwanaga, Kensho, Ly, Ngoc P, McGarry, Meghan E, Church, Gwynne D, Faricy, Lauren E, Rowan, Courtney M, Hume, Janet R, Steiner, Marie E, Crawford, Emily D, Langelier, Charles, Kalantar, Katrina, Chow, Eric D, Miller, Steve, Shimano, Kristen, Melton, Alexis, Yanik, Gregory A, Sapru, Anil, DeRisi, Joseph L
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784263/
https://ncbi.nlm.nih.gov/pubmed/30239621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciy802
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