The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin

Bacillus thuringiensis Cry1Ac toxin binds to midgut proteins, as cadherin (CAD) and ABCC2 transporter, to form pores leading to larval death. In cell lines, co-expression of CAD and ABCC2 enhance Cry1Ac toxicity significantly, but the mechanism remains elusive. Here, we show that the expression of H...

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Publicado en:Toxins (Basel)
Autores principales: Ma, Yuemin, Zhang, Jianfeng, Xiao, Yutao, Yang, Yanchao, Liu, Chenxi, Peng, Rong, Yang, Yongbo, Bravo, Alejandra, Soberón, Mario, Liu, Kaiyu
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6784258/
https://ncbi.nlm.nih.gov/pubmed/31540044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11090538
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