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The Conserved Tyr176/Leu177 Motif in the α-Helix 9 of the Feline Immunodeficiency Virus Capsid Protein Is Critical for Gag Particle Assembly

The capsid domain (CA) of the lentiviral Gag polyproteins has two distinct roles during virion morphogenesis. As a domain of Gag, it mediates the Gag–Gag interactions that drive immature particle assembly, whereas as a mature protein, it self-assembles into the conical core of the mature virion. Len...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Viruses
Main Authors: Ovejero, César A., González, Silvia A., Affranchino, José L.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783973/
https://ncbi.nlm.nih.gov/pubmed/31487820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11090816
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