Bitter Taste Receptors (TAS2Rs) in Human Lung Macrophages: Receptor Expression and Inhibitory Effects of TAS2R Agonists

BACKGROUND: Bitter-taste receptors (TAS2Rs) are involved in airway relaxation but are also expressed in human blood leukocytes. We studied TAS2R expression and the effects of TAS2R agonists on the lipopolysaccharide (LPS)-induced cytokine release in human lung macrophages (LMs). METHODS: Lung macrop...

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Udgivet i:Front Physiol
Main Authors: Grassin-Delyle, Stanislas, Salvator, Hélène, Mantov, Nikola, Abrial, Charlotte, Brollo, Marion, Faisy, Christophe, Naline, Emmanuel, Couderc, Louis-Jean, Devillier, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Physiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783802/
https://ncbi.nlm.nih.gov/pubmed/31632299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01267
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