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Dynorphin‐based “release on demand” gene therapy for drug‐resistant temporal lobe epilepsy

Focal epilepsy represents one of the most common chronic CNS diseases. The high incidence of drug resistance, devastating comorbidities, and insufficient responsiveness to surgery pose unmet medical challenges. In the quest of novel, disease‐modifying treatment strategies of neuropeptides represent...

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Detalles Bibliográficos
Publicado en:EMBO Mol Med
Main Authors: Agostinho, Alexandra S, Mietzsch, Mario, Zangrandi, Luca, Kmiec, Iwona, Mutti, Anna, Kraus, Larissa, Fidzinski, Pawel, Schneider, Ulf C, Holtkamp, Martin, Heilbronn, Regine, Schwarzer, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783645/
https://ncbi.nlm.nih.gov/pubmed/31486590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809963
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