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E. coli primase and DNA polymerase III holoenzyme are able to bind concurrently to a primed template during DNA replication

During DNA replication in E. coli, a switch between DnaG primase and DNA polymerase III holoenzyme (pol III) activities has to occur every time when the synthesis of a new Okazaki fragment starts. As both primase and the χ subunit of pol III interact with the highly conserved C-terminus of single-st...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bogutzki, Andrea, Naue, Natalie, Litz, Lidia, Pich, Andreas, Curth, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783573/
https://ncbi.nlm.nih.gov/pubmed/31595021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51031-0
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