Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer

Enhancer RNA (eRNA) is a type of noncoding RNA transcribed from the enhancer. Although critical roles of eRNA in gene transcription control have been increasingly realized, the systemic landscape and potential function of eRNAs in cancer remains largely unexplored. Here, we report the integration of...

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Publicado en:Nat Commun
Autores principales: Zhang, Zhao, Lee, Joo-Hyung, Ruan, Hang, Ye, Youqiong, Krakowiak, Joanna, Hu, Qingsong, Xiang, Yu, Gong, Jing, Zhou, Bingying, Wang, Li, Lin, Chunru, Diao, Lixia, Mills, Gordon B., Li, Wenbo, Han, Leng
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783481/
https://ncbi.nlm.nih.gov/pubmed/31594934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12543-5
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