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Mutational Spectrum of Spast (Spg4) and Atl1 (Spg3a) Genes In Russian Patients With Hereditary Spastic Paraplegia

Hereditary spastic paraplegia (HSP) comprises a heterogeneous group of neurodegenerative disorders, it share common symptom - of progressive lower spastic paraparesis. The most common autosomal dominant (AD) forms of HSP are SPG4 (SPAST gene) and SPG3 (ATL1 gene). In the current research we investig...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kadnikova, V. A., Rudenskaya, G. E., Stepanova, A. A., Sermyagina, I. G., Ryzhkova, O. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783457/
https://ncbi.nlm.nih.gov/pubmed/31594988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50911-9
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