Peri-adolescent alcohol consumption increases sensitivity and dopaminergic response to nicotine during adulthood in female alcohol-preferring (P) rats: alterations to α7 nicotinic acetylcholine receptor expression

Adolescent alcohol drinking has been linked to increased risk for drug abuse during adulthood. Nicotine microinjected directly into the posterior ventral tegmental area (pVTA) stimulates dopamine (DA) release in the nucleus accumbens (NAc) shell. The α7 nicotinic acetylcholine receptor (nAChR) is a...

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Veröffentlicht in:Behav Brain Res
Hauptverfasser: Waeiss, Robert A., Knight, Christopher P., Carvajal, Gustavo B., Bell, Richard L., Engleman, Eric A., McBride, William J., Hauser, Sheketha R., Rodd, Zachary A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783378/
https://ncbi.nlm.nih.gov/pubmed/31473285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2019.112190
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