Identification of an increased alveolar macrophage subpopulation in old mice that displays unique inflammatory characteristics and is permissive to Mycobacterium tuberculosis infection

The elderly population is more susceptible to pulmonary infections including tuberculosis. Herein, we characterize the impact of aging on the phenotype of mouse alveolar macrophages (AMs) and their response to Mycobacterium tuberculosis (M.tb). Uninfected AMs were isolated from bronchoalveolar lavag...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Lafuse, William P., Rajaram, Murugesan V.S., Wu, Qian, Moliva, Juan I., Torrelles, Jordi B., Turner, Joanne, Schlesinger, Larry S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783358/
https://ncbi.nlm.nih.gov/pubmed/31511357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900495
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