Effects of the Sodium Channel Blocker Tetrodotoxin on Acute White Matter Pathology After Experimental Contusive Spinal Cord Injury

Focal microinjection of tetrodotoxin (TTX), a potent voltage-gated sodium channel blocker, reduces neurological deficits and tissue loss after spinal cord injury (SCI). Significant sparing of white matter (WM) is seen at 8 weeks after injury and is correlated to a reduction in functional deficits. T...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Rosenberg, Lisa J., Teng, Yang D., Wrathall, Jean R.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1999
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783088/
https://ncbi.nlm.nih.gov/pubmed/10407048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-14-06122.1999
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