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Optic Nerve Crush: Axonal Responses in Wild-Type and bcl-2 Transgenic Mice

Retinal ganglion cells of transgenic mice overexpressing the anti-apoptotic protein Bcl-2 in neurons show a dramatic increase of survival rate after axotomy. We used this experimental system to test the regenerative potentials of central neurons after reduction of nonpermissive environmental factors...

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Publicat a:J Neurosci
Autors principals: Chierzi, Sabrina, Strettoi, Enrica, Cenni, Maria Cristina, Maffei, Lamberto
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783029/
https://ncbi.nlm.nih.gov/pubmed/10493738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-19-08367.1999
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