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Targeted Expression of Truncated Glued Disrupts Giant Fiber Synapse Formation in Drosophila

Glued(1)(Gl(1)) mutants produce a truncated protein that acts as a poison subunit and disables the cytoplasmic retrograde motor dynein. Heterozygous mutants have axonal defects in the adult eye and the nervous system. Here we show that selective expression of the poison subunit in neurons of the gia...

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Pubblicato in:J Neurosci
Autori principali: Allen, Marcus J., Shan, Xiaoliang, Caruccio, Phyllis, Froggett, Stephan J., Moffat, Kevin G., Murphey, R. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782895/
https://ncbi.nlm.nih.gov/pubmed/10531442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-21-09374.1999
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