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Mapping Quantitative Trait Loci for Seizure Response to a GABA(A) Receptor Inverse Agonist in Mice

To define the genetic contributions affecting individual differences in seizure threshold, a β carboline [methyl-β-carboline-3-carboxylate (β-CCM)]-induced model of generalized seizures was genetically dissected in mice. β-CCM is a GABA(A) receptor inverse agonist and convulsant. By measuring the la...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gershenfeld, Howard K., Neumann, Paul E., Li, Xiaohua, St. Jean, Pamela L., Paul, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782732/
https://ncbi.nlm.nih.gov/pubmed/10234005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-10-03731.1999
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