Developing Schwann Cells Acquire the Ability to Survive without Axons by Establishing an Autocrine Circuit Involving Insulin-Like Growth Factor, Neurotrophin-3, and Platelet-Derived Growth Factor-BB

Although Schwann cell precursors from early embryonic nerves die in the absence of axonal signals, Schwann cells in older nerves can survive in the absence of axons in the distal stump of transected nerves. This is crucially important, because successful axonal regrowth in a damaged nerve depends on...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Meier, Carola, Parmantier, Eric, Brennan, Angela, Mirsky, Rhona, Jessen, Kristjan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782711/
https://ncbi.nlm.nih.gov/pubmed/10234017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-10-03847.1999
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