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Altered Formation of Hemichannels and Gap Junction Channels Caused by C-Terminal Connexin-32 Mutations

Hexamers of connexins (Cxs) form hemichannels that dock tightly in series via their extracellular domains to give rise to gap junction channels. Here we examined the ability of a variety of C-terminal Cx32 mutations, most of which have been identified in X-linked Charcot–Marie–Tooth disease, to form...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Castro, Carmen, Gómez-Hernandez, Juan M., Silander, Kaisa, Barrio, Luis C.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782695/
https://ncbi.nlm.nih.gov/pubmed/10234007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-10-03752.1999
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