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Inhibition of Dentate Granule Cell Neurogenesis with Brain Irradiation Does Not Prevent Seizure-Induced Mossy Fiber Synaptic Reorganization in the Rat

Aberrant reorganization of dentate granule cell axons, the mossy fibers, occurs in human temporal lobe epilepsy and rodent epilepsy models. Whether this plasticity results from the remodeling of preexisting mossy fibers or instead reflects an abnormality of developing dentate granule cells is unknow...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Parent, Jack M., Tada, Eiji, Fike, John R., Lowenstein, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782627/
https://ncbi.nlm.nih.gov/pubmed/10341251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-11-04508.1999
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