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A Dominant Negative Receptor for Specific Secreted Semaphorins Is Generated by Deleting an Extracellular Domain from Neuropilin-1

Neuropilins have recently been characterized as receptors for secreted semaphorins. Here, we report the generation of a dominant negative form of neuropilin-1 by the deletion of one of its extracellular domains. Expression of this variant in cultured primary sympathetic neurons blocks the paralysis...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Renzi, Michael J., Feiner, Leonard, Koppel, Adam M., Raper, Jonathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782461/
https://ncbi.nlm.nih.gov/pubmed/10479689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-18-07870.1999
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