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Vesicular Monoamine Transporter-2 and Aromaticl-Amino Acid Decarboxylase Enhance Dopamine Delivery afterl-3,4-Dihydroxyphenylalanine Administration in Parkinsonian Rats

Medical therapy in Parkinson’s disease (PD) is limited by the short-duration response and development of dyskinesia that result from chronic l-3,4-dihydroxyphenylalanine (l-DOPA) therapy. These problems occur partly because the loss of dopamine storage sites leads to erratic dopamine delivery. Vesic...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Lee, Won Yong, Chang, Jin Woo, Nemeth, Nicole L., Kang, Un Jung
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782290/
https://ncbi.nlm.nih.gov/pubmed/10191339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-08-03266.1999
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