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Overexpression of α-Internexin Causes Abnormal Neurofilamentous Accumulations and Motor Coordination Deficits in Transgenic Mice

α-Internexin is the first neuronal intermediate filament (IF) protein expressed in postmitotic neurons of the developing nervous system. In the adult, its expression is restricted to mature neurons in the CNS. To study the potential role of α-internexin in neurodegeneration, we have generated transg...

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Publicat a:J Neurosci
Autors principals: Ching, Gee Y., Chien, Chung-Liang, Flores, Roberto, Liem, Ronald K. H.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782284/
https://ncbi.nlm.nih.gov/pubmed/10191315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-08-02974.1999
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