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Overexpression of α-Internexin Causes Abnormal Neurofilamentous Accumulations and Motor Coordination Deficits in Transgenic Mice

α-Internexin is the first neuronal intermediate filament (IF) protein expressed in postmitotic neurons of the developing nervous system. In the adult, its expression is restricted to mature neurons in the CNS. To study the potential role of α-internexin in neurodegeneration, we have generated transg...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ching, Gee Y., Chien, Chung-Liang, Flores, Roberto, Liem, Ronald K. H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782284/
https://ncbi.nlm.nih.gov/pubmed/10191315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-08-02974.1999
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