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Brain-Derived Neurotrophic Factor Mediates the Anti-Apoptotic Effect of NMDA in Cerebellar Granule Neurons: Signal Transduction Cascades and Site of Ethanol Action

Cerebellar granule neurons cultured in medium containing a physiological concentration of KCl (5 mm) undergo apoptosis. The cells can be rescued by the in vitroaddition of NMDA. The protective effect of NMDA is thought to reflect the in vivo innervation of developing cerebellar granule neurons by gl...

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Pubblicato in:J Neurosci
Autori principali: Bhave, Sanjiv V., Ghoda, Lucy, Hoffman, Paula L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782254/
https://ncbi.nlm.nih.gov/pubmed/10212287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-09-03277.1999
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