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A Role for MAPK/ERK in Sympathetic Neuron Survival: Protection against a p53-Dependent, JNK-Independent Induction of Apoptosis by Cytosine Arabinoside

The antimitotic nucleoside cytosine arabinoside (araC) causes apoptosis in postmitotic neurons for which two mechanisms have been suggested: (1) araC directly inhibits a trophic factor-maintained signaling pathway required for survival, effectively mimicking trophic factor withdrawal; and (2) araC i...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Anderson, Christopher N. G., Tolkovsky, Aviva M.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782192/
https://ncbi.nlm.nih.gov/pubmed/9880587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-02-00664.1999
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