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Ionic Currents Underlying Spontaneous Action Potentials in Isolated Cerebellar Purkinje Neurons

Acutely dissociated cell bodies of mouse Purkinje neurons spontaneously fired action potentials at ∼50 Hz (25°C). To directly measure the ionic currents underlying spontaneous activity, we voltage-clamped the cells using prerecorded spontaneous action potentials (spike trains) as voltage commands an...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Raman, Indira M., Bean, Bruce P.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782167/
https://ncbi.nlm.nih.gov/pubmed/10024353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-05-01663.1999
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