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Lectin-Induced Inhibition of Desensitization of the Kainate Receptor GluR6 Depends on the Activation State and Can Be Mediated by a Single Native or Ectopic N-Linked Carbohydrate Side Chain

The ionotropic glutamate receptor GluR6 exhibits strongly and rapidly desensitizing current responses. Treatment of heterologically expressed GluR6 with the lectin concanavalin A (ConA) inXenopus oocytes as well as in human embryonic kidney-293 cells results in a considerable increase of the steady-...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Everts, Inga, Petroski, Robert, Kizelsztein, Pablo, Teichberg, Vivian I., Heinemann, Stephen F., Hollmann, Michael
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782145/
https://ncbi.nlm.nih.gov/pubmed/9920655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-03-00916.1999
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