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Midostaurin In Acute Myeloid Leukemia: An Evidence-Based Review And Patient Selection

Fms-related-tyrosine kinase 3 (FLT3) mutations occur in approximately a third of acute myeloid leukemia (AML) patients and confer an adverse prognosis. Numerous studies have evaluated FLT3 targeting as single agent and in combination approaches in frontline and relapsed AML. At this time, midostauri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Manag Res
Hauptverfasser: Abbas, Hussein A, Alfayez, Mansour, Kadia, Tapan, Ravandi-Kashani, Farhad, Daver, Naval
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782026/
https://ncbi.nlm.nih.gov/pubmed/31632141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S177894
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