Hearing consequences in Gjb2 knock-in mice: implications for human p.V37I mutation

Human p.V37I mutation of GJB2 gene was strongly correlated with late-onset progressive hearing loss, especially among East Asia populations. We generated a knock-in mouse model based on human p.V37I variant (c.109G>A) that recapitulated the human phenotype. Cochlear pathology revealed no signific...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Lin, Xin, Li, Gen, Zhang, Yu, Zhao, Jingjing, Lu, Jiawen, Gao, Yunge, Liu, Huihui, Li, Geng-Lin, Yang, Tao, Song, Lei, Wu, Hao
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6782001/
https://ncbi.nlm.nih.gov/pubmed/31562289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102246
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