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Mutations in the PCNA DNA Polymerase Clamp of Saccharomyces cerevisiae Reveal Complexities of the Cell Cycle and Ploidy on Heterochromatin Assembly

In Saccharomyces cerevisiae, transcriptional silencing at HML and HMR maintains mating-type identity. The repressive chromatin structure at these loci is replicated every cell cycle and must be re-established quickly to prevent transcription of the genes at these loci. Mutations in a component of th...

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Vydáno v:Genetics
Hlavní autoři: Brothers, Molly, Rine, Jasper
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781887/
https://ncbi.nlm.nih.gov/pubmed/31451562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302452
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