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Possible role of BMP-4 in the hyper-pigmentation of psoriatic plaques after anti-TNF-α treatment
Psoriasis over-expresses several inflammatory mediators, which impacts the activity of melanocytes. Tyrosinase (Tyr) and microphthalmia-associated transcription factor (MITF) are the primary regulators of melanogenesis. Furthermore, bone morphogenetic proteins (BMPs) modulate various pathobiologic p...
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| Publicado en: | Exp Ther Med |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
D.A. Spandidos
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6781796/ https://ncbi.nlm.nih.gov/pubmed/31611943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.8015 |
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