Possible role of BMP-4 in the hyper-pigmentation of psoriatic plaques after anti-TNF-α treatment

Psoriasis over-expresses several inflammatory mediators, which impacts the activity of melanocytes. Tyrosinase (Tyr) and microphthalmia-associated transcription factor (MITF) are the primary regulators of melanogenesis. Furthermore, bone morphogenetic proteins (BMPs) modulate various pathobiologic p...

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Publicado en:Exp Ther Med
Main Authors: Di Costanzo, Luisa, Scala, Emanuele, Caiazzo, Giuseppina, Lembo, Serena, Marino, Rita, Megna, Matteo, Patrì, Angela, Di Caprio, Roberta, Balato, Anna
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2019
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781796/
https://ncbi.nlm.nih.gov/pubmed/31611943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.8015
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