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An Injectable Click-Crosslinked Hydrogel that Prolongs Dexamethasone Release from Dexamethasone-Loaded Microspheres

Our purpose was to test whether a preparation of injectable formulations of dexamethasone (Dex)-loaded microspheres (Dex-Ms) mixed with click-crosslinked hyaluronic acid (Cx-HA) (or Pluronic (PH) for comparison) prolongs therapeutic levels of released Dex. Dex-Ms were prepared using a monoaxial-nozz...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Heo, Ji Yeon, Noh, Jung Hyun, Park, Seung Hun, Ji, Yun Bae, Ju, Hyeon Jin, Kim, Da Yeon, Lee, Bong, Kim, Moon Suk
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781549/
https://ncbi.nlm.nih.gov/pubmed/31480552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11090438
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