Hair follicle regeneration suppresses Ras-driven oncogenic growth

Mutations associated with tumor development in certain tissues can be nontumorigenic in others, yet the mechanisms underlying these different outcomes remains poorly understood. To address this, we targeted an activating Hras mutation to hair follicle stem cells and discovered that Hras mutant cells...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cell Biol
Egile Nagusiak: Pineda, Cristiana M., Gonzalez, David G., Matte-Martone, Catherine, Boucher, Jonathan, Lathrop, Elizabeth, Gallini, Sara, Fons, Nathan R., Xin, Tianchi, Tai, Karen, Marsh, Edward, Nguyen, Don X., Suozzi, Kathleen C., Beronja, Slobodan, Greco, Valentina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781447/
https://ncbi.nlm.nih.gov/pubmed/31488583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907178
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