Hair follicle regeneration suppresses Ras-driven oncogenic growth

Mutations associated with tumor development in certain tissues can be nontumorigenic in others, yet the mechanisms underlying these different outcomes remains poorly understood. To address this, we targeted an activating Hras mutation to hair follicle stem cells and discovered that Hras mutant cells...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Pineda, Cristiana M., Gonzalez, David G., Matte-Martone, Catherine, Boucher, Jonathan, Lathrop, Elizabeth, Gallini, Sara, Fons, Nathan R., Xin, Tianchi, Tai, Karen, Marsh, Edward, Nguyen, Don X., Suozzi, Kathleen C., Beronja, Slobodan, Greco, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781447/
https://ncbi.nlm.nih.gov/pubmed/31488583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201907178
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