Wird geladen...
A modifier in the 129S2/SvPasCrl genome is responsible for the viability of Notch1[12f/12f] mice
BACKGROUND: Mouse NOTCH1 carries a highly conserved O-fucose glycan at Thr466 in epidermal growth factor-like repeat 12 (EGF12) of the extracellular domain. O-Fucose at this site has been shown by X-ray crystallography to be recognized by both DLL4 and JAG1 Notch ligands. We previously showed that a...
Gespeichert in:
| Veröffentlicht in: | BMC Dev Biol |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6781419/ https://ncbi.nlm.nih.gov/pubmed/31590629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-019-0199-3 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|