A local score approach improves GWAS resolution and detects minor QTL: application to Medicago truncatula quantitative disease resistance to multiple Aphanomyces euteiches isolates

Quantitative trait loci (QTL) with small effects, which are pervasive in quantitative phenotypic variation, are difficult to detect in genome-wide association studies (GWAS). To improve their detection, we propose to use a local score approach that accounts for the surrounding signal due to linkage...

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Veröffentlicht in:Heredity (Edinb)
Hauptverfasser: Bonhomme, Maxime, Fariello, Maria Inés, Navier, Hélène, Hajri, Ahmed, Badis, Yacine, Miteul, Henri, Samac, Deborah A., Dumas, Bernard, Baranger, Alain, Jacquet, Christophe, Pilet-Nayel, Marie-Laure
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781128/
https://ncbi.nlm.nih.gov/pubmed/31138867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41437-019-0235-x
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