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Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells

Renieramycin M (RM) is a KCN-stabilized tetrahydroisoquinoline purified from the blue sponge Xestospongia sp., with nanomolar IC(50)s against several cancer cell lines. Our goal is to evaluate its combination effects with doxorubicin (DOX) in estrogen receptor positive MCF-7 breast cancer cells. MCF...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Tun, Jortan O., Salvador-Reyes, Lilibeth A., Velarde, Michael C., Saito, Naoki, Suwanborirux, Khanit, Concepcion, Gisela P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780817/
https://ncbi.nlm.nih.gov/pubmed/31527453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17090536
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