The Mitochondrial Antioxidant SS-31 Modulates Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Type 2 Diabetes

Mitochondrial dysfunction has been shown to play a central role in the pathophysiology of type 2 diabetes (T2D), and mitochondria-targeted agents such as SS-31 are emerging as a promising strategy for its treatment. We aimed to study the effects of SS-31 on leukocytes from T2D patients by evaluating...

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Bibliographic Details
Published in:J Clin Med
Main Authors: Escribano-López, Irene, de Marañon, Aranzazu M, Iannantuoni, Francesca, López-Domènech, Sandra, Abad-Jiménez, Zaida, Díaz, Pedro, Solá, Eva, Apostolova, Nadezda, Rocha, Milagros, Víctor, Víctor M
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780723/
https://ncbi.nlm.nih.gov/pubmed/31466264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8091322
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