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Therapeutic targeting of the crosstalk between cancer-associated fibroblasts and cancer stem cells

Cancer-associated fibroblasts (CAFs) play critical roles in cancer progression and treatment failure. CAFs display extreme phenotypic heterogeneity and functional diversity. Some subpopulations of CAFs have the ability to reconstitute cancer stemness by promoting the expansion of cancer stem cells (...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Huang, Tu-Xiong, Guan, Xin-Yuan, Fu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780671/
https://ncbi.nlm.nih.gov/pubmed/31598393
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