Poly(Cyclohexene Phthalate) Nanoparticles for Controlled Dasatinib Delivery in Breast Cancer Therapy

The effect on the activity in breast cancer models of the small tyrosine kinase inhibitor dasatinib (DAS), either alone or in combination with other antitumoral agents, has been recently explored. However, DAS is characterized by its low and highly pH-dependent solubility, which could lead to poor u...

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Publicat a:Nanomaterials (Basel)
Autors principals: Niza, Enrique, Nieto-Jiménez, Cristina, Noblejas-López, María del Mar, Bravo, Iván, Castro-Osma, José Antonio, de la Cruz-Martínez, Felipe, Martínez de Sarasa Buchaca, Marc, Posadas, Inmaculada, Canales-Vázquez, Jesús, Lara-Sanchez, Agustín, Hermida-Merino, Daniel, Solano, Eduardo, Ocaña, Alberto, Alonso-Moreno, Carlos
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780527/
https://ncbi.nlm.nih.gov/pubmed/31461998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano9091208
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