Total Syntheses and Preliminary Biological Evaluation of Brominated Fascaplysin and Reticulatine Alkaloids and Their Analogues

A simple approach toward the synthesis of the marine sponge derived pigment fascaplysin was used to obtain the marine alkaloids 3-bromofascaplysin and 3,10-dibromofascaplysin. These compounds were used for first syntheses of the alkaloids 14-bromoreticulatate and 14-bromoreticulatine. Preliminary bi...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Zhidkov, Maxim E., Smirnova, Polina A., Tryapkin, Oleg A., Kantemirov, Alexey V., Khudyakova, Yuliya V., Malyarenko, Olesya S., Ermakova, Svetlana P., Grigorchuk, Valeria P., Kaune, Moritz, von Amsberg, Gunhild, Dyshlovoy, Sergey A.
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780422/
https://ncbi.nlm.nih.gov/pubmed/31450717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17090496
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