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Mitochondrial protection by simvastatin against angiotensin II‐mediated heart failure
BACKGROUND AND PURPOSE: Mitochondrial dysfunction plays a role in the progression of cardiovascular diseases including heart failure. 3‐Hydroxy‐3‐methylglutaryl‐CoA reductase inhibitors (statins), which inhibit ROS synthesis, show cardioprotective effects in chronic heart failure. However, the benef...
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| 出版年: | Br J Pharmacol |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6780047/ https://ncbi.nlm.nih.gov/pubmed/31265743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14781 |
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